This research article provides a comparative overview of Ayurveda and Unani, two traditional systems of medicine that have been practiced in India and the Middle East for centuries. The efficiency and limitations of both systems are discussed with reference to their historical development, theoretical frameworks, diagnostic and treatment methods, and current practices. The methodology involved a literature review of scholarly articles, books, and online resources that discuss Ayurveda and Unani. The results and discussion section highlight the similarities and differences between the two systems, and their strengths and weaknesses. The article concludes that both Ayurveda and Unani have their own unique contributions to make to the field of traditional medicine and that a better understanding of their theoretical frameworks and clinical practices can enhance the efficacy of their treatment modalities.