Chronic non-communicable diseases are assuming increasing importance among the adult population in both developed and developing countries. A large percentage of NCDs are preventable through the changes in the lifestyle. The leading cause of NCD death in 2012 were: cardiovascular diseases (17.5 million deaths or 46.2 per cent of NCD death), cancer (8.2 million or 21.7 per cent of NCD deaths), respiratory diseases, including asthma and chronic obstructive pulmonary disease (4 million or 10.7 per cent of NCD deaths), and diabetes (1.5 million or 4 per cent of NCD deaths). The preventive attack on chronic diseases is based on the knowledge that they are multi-factorial in causation, so their prevention demand a complex mix of interventions. Some of the interventions that should be undertaken immediately to produce accelerated results in term of lives saved, disease prevented and heavy cost avoided are as follow:- Restrictions on marketing of foods and beverages high in salt, fats and sugar. It is important to have knowledge regarding NCDs from childhood period. So the present study was taking up to assess the knowledge regarding the prevention of non-communicable diseases. Healthy nutrition environments in schools. Nutrition information and counselling in health care and national physical activity guidelines. Objectives: The study aimed to determine the level of knowledge regarding the prevention of non-communicable diseases. To determine the association between knowledge regarding prevention of NCDs with selected socio-demographic variables. To develop and provide the information booklet for prevention of non– communicable diseases (NCDs) to the students of selected schools of district Sirmour. Method: Descriptive research design was adopted to collect data from 380 students of the selected schools of District Sirmour (H.P.) using the convenient sampling technique. Data was collected by knowledge questionnaire. Result: Result revealed that the present study findings showed that 87.9% of the students were having average knowledge, 9.5% were having poor knowledge and 2.6% were having good knowledge. There is significant association between age, gender, type of family, residence, family history of any NCDs. p-value <0.05 level of significant. Conclusion: The study concluded that most of the students had average knowledge, which needs to be increased. With regard to this view, an information booklet was given to the study students.