A study to assess the effectiveness of structured teaching programme on knowledge regarding revised immunization schedule among mothers of under five age children in selected hospital at selected city.”Objectives: To assess the existing knowledge of mothers regarding revised immunization schedule and to evaluate effectiveness of structured teaching programme on knowledge regarding revised immunization schedule. And To find out the association between pre-test knowledge score with selected demographic variables. Methodology: quantitative research approach was used with quasi experimental one group pre-test and post- test design. Population50 Mothers of under Five Age Children, Purposive Sampling Technique was used for data collection. Result: In the pre-test- 6 (12%) had inadequate knowledge, maximum 44 (88%) had moderately adequate knowledge and no one mothers of under five age children had adequate knowledge regarding revised immunization schedule. In post-test- maximum 47 (94%) Mothers of under-five age children were having adequate knowledge and no one mothers of under-five age children were having inadequate knowledge and remaining 3 (6%) Of mothers of under-five age children were having moderately adequate knowledge regarding revised immunization schedule.