In the field of inorganic separation, the incentive to explore the use of non-aqueous or mixed solvent has been enhanced selectivity’s, discovered quite early in such media for Zeolites [1] and ion exchange resins [2]. The partial substitution of an aqueous solution by organic solvent produces a number of changes in an exchange system. The electrolyte plays a significant role in the ion exchange equilibrium with aqueous solutions. This effect is expected to be even more important in the adsorption equilibriums of metal ions from mixed aqueous organic solvents. Adsorption equilibrium depends on the properties of the organic solvent and the reaction with resin and electrolytes which determine the equilibrium. The metal ion exchange on cation exchangers and their uses has been done.