Ayurveda is a science of life that deals with keeping the body and mind healthy, by protecting them against diseases and curing illness through its various principles. Certain aspects like Dincharya, Ritucharya, Aahara Vidhi Vidhana, Na Vegadharneeya, etc. are given in classical literature to keep one in a healthy state. The concept of Vega in contemporary science, can be compared to natural biological reflexes related to the autonomous nervous system and their suppression will result in Vata aggravation and ultimately may lead to various pathologies in the body. In the present era, because of stressful jobs, due to hesitation, no proper facilities to void, and being engaged in important work, a person may suppress various urges. Ayurveda describes fourteen Vegas and their suppression or premature initiation is a key factor in the manifestation of ailments through disturbance in the equilibrium of Doshas. In this article, diseases produced in the human body by suppressing natural urges as given in the text are discussed along with their treatment and an attempt is made to analyze pathophysiological changes in different organ systems.