Nyctanthes arbotristis is a medicinal plant found in South Asia and Southeast Asia. .It was revealed that the plant exhibits various pharmacological activities because of the presence of secondary metabolites compounds. It exhibits different pharmacological activities like anticancer, antipyretic, antihistaminic, antibacterial, anti-inflammatory, antioxidant, antiviral and antifungal activities have been reported. This present review compiles the different phytochemical compounds and pharmacological activities reported so far by this plant in a comprehensive manner.