Anticipating the Thyroid disease is one of the currents focuses in Medical research. The most difficult undertaking of the restorative field is to give the infection analysis at the beginning period with higher precision. The sickness forecast assumes a critical part in information mining. Information mining is mostly utilized as a part of medicinal service associations for basic leadership, diagnosing malady and giving better treatment to the patients. It is a procedure for investigating huge informational collections to discover a few examples. These examples can be useful for forecast demonstrating. In this theory, the principal objective is an order of thyroid ailment. An investigation of thyroid sickness finding systems utilized as a part of information mining. The thyroid is one of the impulsive syndromes in the restorative field. Thyroid hormones control the body's metabolic rate. Also, information mining methods have been connected in different areas the order, after the effects of the restorative informational index which helps the method for medications to the patients. In proposing a procedure, look at different calculations, for example, naval forces' bayer, random backwoods, irregular tree, REP Tree, D tree to discover which calculation to give the best outcome for thyroid ailment expectation. An exploratory examination is conveyed out our calculation to accomplish better exactness. There are numerous information mining grouping Algorithms, for example, naval forces, REP Tree, arbitrary tree, irregular forest, D tree and k-overlap cross approval et cetera. The proposed Algorithm gives exactness 99.80% with cross approval k=6.