Ayurveda is not only medicine but it is a science of life which guides us about healthy regimens to live healthy happy and long life. The Shodhana or Detoxification remedies which will get rid of the vitiated toxins present in the physique in terms of Vamanadi measures. According to seasons, their dosha will get vitiated in the body which may additionally in flip leads to a one-of-a-kind disease. If one takes care of this by performing Shodhana (Shodhana) in each season may additionally pacify the vitiated dosha and help in stopping the ailment, these will act as preventive, promotive and curative. This article enlightens about exclusive Detoxification treatment plans carried out in accordance to extraordinary seasons.