Diabetes is a complex disease charged by susceptible to chronic disease of management and prevention of complications among adult diabetic clients. Diabetes care aims to achieve a quality of life and life expectancy similar to that of the general population by reducing the risk of complications. A study was undertaken to assess the knowledge regarding the management and prevention of complications of diabetes mellitus among adult diabetic clients in a selected urban area. Objectives 1). To assess the knowledge regarding management and prevention of complications among the adult diabetic client. 2) To find out the association between the knowledge score with selected demographic variables. Materials and method- the descriptive study was conducted on 100 diabetic clients were non probability purposive sampling technique used and a structured knowledge and prevention questionnaire was used to assess the knowledge. The result of the study revealed that the age range of subjects was between 51-60 years belonging to 30% .40 % of clients had diabetes for more than 3 years, majority of 88% of clients were treated only with an oral hypoglycaemic agent and 46 % of them had experienced any one or more of diabetes-related complication, 52% of them had Inadequate knowledge, 41 % had moderate knowledge and 7 % had lack of knowledge on management and prevention of complications of diabetes mellitus.