Difficulties with clinical trial recruitment severely hamper research advancement and the generalizability of study results. The research site may take a lot of time and effort to enroll participants in clinical studies. Every research is unique in several ways, including stages, study indications, eligibility requirements, etc. When determining the enrollment deadline, the potential duration of the trial is usually based on the study's indication and the accessibility of the patient population in the research site's geographic region. Every clinical trial's success depends on its ability to recruit and retain patients, yet these efforts are under extreme strain globally. Patients also have concerns and face significant challenges when participating in clinical trials, such as lack of trust, communication, family support, fear of side effects, etc. This manuscript explores the differences between barriers to recruitment and concerns about participation It consists of a survey intended to collect information on these matters. The collected data is then analyzed and presented using graphs and charts to illustrate the results.