Siddhar Yogam or Siddhar Yoga Muraigal are the ancient methods that were advocated by the Siddhars in order to prevent the ailments occurring due to human aging. Also, these methods consisted of physical, mental, and even dietary practices, that must be practiced for a period of a mandala (48 days). The dietary practices, that were advocated by them are the ‘Kaayakarpam’ practices. These usually include the intake of a certain poly or monoherbal drug, for a stipulated span of time. They may either be the drug of choice for general body wellness, or for a specific disease. Considering Amukkara Podi (the powdered root of Withania Somnifera), it has several references as a Kaayakarpam[1] drug for general body wellness. As a special drug, it acts wonderfully towards weight loss for obese patients, when taken in with honey. Obesity[2] or being obese is a health disorder that is characterized by the presence of a BMI of more than 25. These patients tend to be overweight, have a lethargic attitude or a condition of tiredness towards work, and at later stages may suffer from knee, hip pains, etc. Obesity has also been considered to be an uprising health disorder of concern by WHO. The treatment generally includes rigorous exercise in order to lose bodyweight. In cases where obese individuals cannot lose weight through exercise, other options could be taken into consideration. One among them is the intake of Amukkara Podi with Honey. This paper reports the biochemical analysis of the drug, ‘Amukkara Podi’, which could be used as a forerunner for the usage of the drug against obesity.