Man is intelligent because of the brain. But the brain, all its knowledge, and power are destroyed after the death of the man. BLUE BRAIN, The name of the world's first virtual brain that means a machine that functions like a human brain. It can think. It can take a decision. It can response. It can store things in memory. The research involves studying slices of living brain tissue using microscopes and patch clamp electrodes. Data is collected about all the many different neuron types. This data is used to build biologically realistic models of neurons and networks of neurons in the cerebral cortex. The simulations are carried out on a Blue Gene Supercomputer built by IBM. In this paper, we concentrate on the application of Blue Brain for "Cracking Neural Code" as well as the use of Blue Brain in "Human memory loss". The neural code refers to how the human brain builds images using electrical patterns and cracking the neural code means finding the patterns and meaning in the noisy activity of the cell ensembles. Human memory loss includes conditions like ‘Alzheimer’ and 'short-term memory loss