Thyroid hormone disorders are the commonest endocrine disorder in India and also the commonest preventable cause of mental retardation. The male and female ratio of the disease ranges from 4:1 to 7:1 Untreated hypothyroidism during pregnancy can lead to delays in growth and intellectual development in the baby. The present study focused on the comparison of prevalence of thyroid disorders on various aspects like Comparison of prevalence of thyroid disorder on the basis of age, on the basis of gender, and on the basis of religion. The clinic-based study was conducted in the clinic Ranchi, in this study 305 patients are taken as samples who visited the clinic for treatment of thyroid disorder (Hypothyroidism, Hyperthyroidism) from year Sept 2015 to Dec 2017. Patients of all ages are included in the study. Out of the 305 patients with a thyroid disorder, 298 patients found to have hypothyroidism (98%) and 7 patients with hyperthyroidism (2%). The comparison of disorders found that hypothyroidism is more prevalent than hyperthyroidism. Thyroid disorder is more prevalent in females than males. There is a high prevalence of thyroid dysfunction in female in Ranchi and need for similar studies from different regions of the country covering larger population are well appreciated.