Every year thousands of buildings are damaged and collapsed and thousands of people become homeless due to the natural calamity Earthquake, which occurs with intensities not less than 3 on the seismic scale. In the present era, the low rise to high rise buildings is constructed due to limited space. Once, this earthquake occurs, its effects these structures most. Huge property loss and human loss occur. In order, to control this some precautions and codes for seismic-resistant building construction are assigned by various countries. In India, IS 1893-2002 provides the rules and precautions for various types of building construction that is seismic resistant. Buildings such as Conventional RC Frame structures are common in practice .but due to highly advanced technologies, beamless slab called Flat slab is in use these days. T Hough flat slab possess many advantages over conventional buildings when dealing with seismicity, the flat slab is far less potentially strong to resist for seismic conditions. In the present work the comparison of Conventional building and Flat slab with Drop in different zones, using ETABS software. Therefore, the characteristics of a seismic behavior of Flat slab and Conventional RC frame building measures for guiding the concept and design of these structures and for improving the performance of buildings during seismic loading. In Present work, a good amount of information regarding parameters such as Storey Displacement, Storey Shear, Overturning Moment, and Storey Drift for Flat Slab and Conventional Slab is provided and its variation of these parameters in different zones is also detailed.