It is not very often seen that a pandemic leading towards an epidemic, but here we are discussing how COVID-19 has the potential to trigger neurological disorders. Fascinating evidence demonstrated that COVID-19 infection is capable of modifying the spectrum of the clinical firm where neurological diseases are manifested due to the infection and also are responsible for the development of long-termed diseases. In this review, we will study how there is a latent relationship between COVID-19 and neurological disorders like Parkinson’s disease (PD), Alzheimer’s (AD), and multiple sclerosis (MS). Specifically, in multiple sclerosis more than age, neuroimmunology related factors influence the cause of this disease. Various studies have shown an association between neurological disorders and COVID-19. The important viewpoint here is to understand the SARS-CoV-2 causing infection which leads to the development of COVID-19 affecting neuro balance.