Development of poultry feed supplements for enhancing productivity and performance The demand for protein source for humans in the form of chicken has been increased. Egg consumption has been recommended every day. So, people much depend on poultry food throughout the world. As per FAO (Food and Agricultural Organization) published data, meat production of 109,970 thousand metric tons in 2014 raised to 111,000 thousand metric tons in 2015 which is a 3% lower annual growth rate compared to the past 10 years. Largest poultry meat production is currently from the United States, China, European Union, and Brazil. As per FAO 2015 published data, it was expected that in 2024 the estimated meat production (x 1000 metric tons) of India will be 3521, which is very less compared to (US 24,424), China (23,112), Brazil (15,702). As per FAO, Egg production (x 1000 metric tons), India stands in the third position with 3835 which is less compared to the USA standing in the second position with 5636 and China at first position with 28,761. Poultry diets are formulated based on the nutrient requirements and their metabolism, checking the availability of nutrients from the feed ingredients, cost-effective. In developing countries, the unavailability of accustomed feedstuffs and an increase in the cost of the available feedstuffs are stopping the poultry productivity and it will be more in the future. So, this type of condition demands the immediate requirement of alternative feedstuffs that can be used on a wide range. To increase the poultry productivity, performance and healthy flocks, feed supplementations or additives are required instead of the daily feed uptake. Feed supplements provide constant energy, essential amino acids, proteins, vitamins and minerals with water or feed. Major feed additives used are Enzymes, Antibiotics, Coccidiostats, pigments, Antioxidants, Antifungals, etc. Antibiotics are used as growth promoters (AGP’s) in the past 50 years. The usage of AGPs in the feed lead to antimicrobial resistance development and passage of antibiotic resistance genes to human microbiota from animals. In this context, the European Union has banned the usage of antibiotics from January 1st, 2006 and made legislation to delete antibiotics from their European Registry of Feed additives. Some countries still using these AGP’s affecting their exports in the global market. AGP’s can be replaced by using direct-fed microbial (probiotics), Prebiotics - Fructooligosaccharides (FOS), mannan oligosaccharides (MOS), organic acids, plant extracts, proteins & peptides etc., The ban of the antibiotics raised the need of more feed supplements that can help in growth, health, productivity in terms of meat and eggs, fighting diseases caused by bacterial, viral, fungal & protozoans and combat the stress during transportation, vaccination, de-beaking, housing conditions, lighting etc., The present usage of feed supplements in the market are negligible. Feed supplements help in overcoming the Feed Conversion Ratio (FCR) issues and improves the feed intake that avoids the wastage. Feed supplements and additives are used in small amounts and careful while mixing with the feed for uniform distribution. The objectives involved in the development of feed additive depend majorly on the selection of individual feed additives and their combination without the loss of their efficacies is a challenge. Finally formulating the essential nutrients and non-nutritive additives that are non-essential but important depending on the requirement in the diet and flock conditions helps in the improvement of health and performance.