A field experiment was conducted during the spring season of 2014-15 on clayey soils of Agriculture Faculty of Baghlan University, to study the effect of different doses of nitrogen and phosphorus on growth, yield, and economics of potato (Solanum tuberosum L.). The experiment was laid in a randomized block design (RBD) comprised of 3 replication and sixteen treatments. Application of Nitrogen 250 kg+Phosphorus 175 kg/ha taller plants (41.83cm), higher number of leaves per plant (30.41 ), number of branches per plant ( 4.73), significantly wider leaf area (113.43 cm), higher tuber weight (216.11 g per plant), number of tuber per plant (4.14) significantly higher tuber yield (14.70 ton/ha) and B:C (5.49).