Preterm birth is now the single most important cause of neonatal deaths and the second leading cause of death in children under 5. A quantitative study was done to assess the effectiveness of the Interventional package on physiological, and neurobehavioral parameters among Preterm admitted to NICU by using a True experimental design.150 preterm babies whose weights were between 1500 grams – 2000 grams were selected by using the nonprobability consecutive sampling technique and were randomly allocated to experimental arms I, II,& III ( 50 each ). Experimental arm I received Auditory stimulation, Experimental arm II received Kinesthetic stimulation & Experimental arm III received Tactile stimulation for 5 minutes (AKTS). Pretest and post-test were done by using a questionnaire to obtain Demographic variables, an observational tool, the Bristol Breastfeeding Assessment tool, and Morgan’s neonatal neurobehavioral examination scale. The statistical value showed that moderately significant difference between the pre and post-test scores of physiological, and neurobehavioral parameters among Preterm.