Among all the chronic diseases, Liver Diseases was ranked as the fifth most common cause of death (National Statistics of UK, 2010). The presence of Ascites is a sign of poor prognosis in patients with Chronic Liver Diseases. So, the aim of the present study was to provide an emphasize on Self-Management of Ascites for patients who are living with Chronic Liver Diseases. For this purpose Quantitative approach with Two groups, Pretest-Posttest designs were adopted and a study conducted in Hepatology OPD, ILBS. A total of 60 patients were enrolled based on sampling criteria and consent has been taken. The data was collected by assessing Knowledge and Attitude with Structured Knowledge Questionnaire and Likert Attitude Scale, respectively. These scales were highly reliable and valid. On the same day of assessment of the Experiment group, the mHealth app was introduced and given to the subjects. MS Excel and SPSS 22.0 were used for analysis. The data obtained were analyzed using Descriptive (Mean, Percentage, and chi-square) and Inferential statistics (Paired t-test, Independent t-test, Karl Pearson’s correlation, and Krushkal Wallis test). The study results showed that the majority of patients in both the Experiment and Comparison group were upper-middle-class, male, aged between 47-60 years, married, and residing in urban areas. Independent t-test was computed which showed a significant (p= 0.04) difference between the post-test Knowledge score of Experiment and Comparison group. In the Experiment group, a statistically significant positive correlation (r=0.37, p=0.04) was found between Posttest Knowledge and Posttest Attitude score. Based on the findings of the study, it is concluded that mHealth app was effective in Self –Management of Ascites in terms of Knowledge of CLD Patients.