Stress is an inevitable word in this fast-spinning technical world. Efficient and Effective performance depends on the better psychological well-being of the employees. A study is conducted to assess the Effectiveness of Relaxation therapy on stress among 120 teachers of mentally disabled children. A quantitative research approach with a pre-experimental one-group pre-test post-test design is adopted. Data collected through self-report using the stress Assessment Scale. The findings revealed that there is a significant reduction of stress (t=23.68,p<0.001) and showed that relaxation therapy is effective in reducing stress.