The purpose of current study was to identify the gender difference in developing loneliness and obsession compulsions symptoms during Covid-19 pandemic. Participants (N=120) including males (n=60) and females (n=60) were selected from Faisalabad city of Punjab, using purposive sampling technique. UCLA Loneliness scale version 3 (Russel, 1996) and Y-BOCS (Goodman et al., 1989 a,b) were used to measure the loneliness and obsession compulsion symptoms. For analytic purpose, independent t- sample test was applied, using Statical Package for Social Science version 26. Findings of analysis indicated that females are more prone to develop loneliness, which is indicated by t =-3.404 at p=.001< .001. Also, females developed more obsession compulsion symptoms as compared to males, which was indicated by t =-3.022 at p=.003 < .001.