In recent years, Wireless Sensor Network (WSN) has led to many new protocols designed for such networks have to be energy aware in order to improve the lifetime of the network. To find an effective and an efficient routing protocol, across whole network topology, is a major issue in networking. So Multi-hop and clustering communication are most efficient routing methods in WSN. Though, cluster heads have to heavy traffic around the Base Station (BS). In this paper, we have implemented a Region Based hybrid multi-hop routing method for heterogeneous WSN in which to use multi-hop communication method for transmission and use fuzzy logic technique for clustering. Simulation results show that our method reduces consumption of energy and enhance the lifetime of network in comparison to other clustering and multi-hop communication methods.