A huge power is dissipated in distribution systems as power losses. The loss reduction and bus voltage improvement are the critical parameters of effective distribution feeder power flow. There are several techniques followed for power loss reduction and voltage profile improvement in distribution systems. Specifically, Distribution Feeder Reconfiguration (DFR) method is employed for the proposed system. The most important criterion of Distribution Feeder Reconfiguration is loss reduction, voltage profile improvement and relieving of the power lines from overloading. The proposed method is tested on a 3-Feeder distribution network and IEEE 33-Bus system. Genetic Algorithm (GA) optimization approach is applied to get the optimal switching scheme for feeder reconfiguration. Simulation results from load flow analysis and GA methodology have shown that the implementation of this method leads to a significant enhancement in voltage profile and reduction in the real power loss. Finally, results of system loss reduction and voltage stability enhancement with a brief overview of approached model are revealed in this paper.