Six Sigma is a well-structured methodology that concentrates on decreasing variation, measuring defects and beneficent the quality of products, processes, and services. Six Sigma methodologies were primarily progressing by Motorola in the 1980s and it targeted a difficult aim of 3.4 parts per million defects. Six Sigma has been on an unbelievable run over 25 years, manufacture important savings to the under the most line of many large and small organizations. This work presents the step-by-step application of the Six Sigma (acquaint, Measure, Analysis, progress, and monitoring) approach to eliminate the defects in injection moulding process this has helped to decrease defects in the process and thereby progress productivity.