Hospital Acquired Infections (HAI) are a major global safety concern for both patients as well as healthcare professionals. Many factors promote infection among hospitalized patients – decreased immunity among patients; increasing variety of medical procedures and invasive techniques creating potential routes of infection; and the transmission of the drug-resistant bacteria among the crowded hospital populations where poor infection control practices can facilitate transmission. Dental care providers, in particular, are also at an increased risk as they are providing care by working with sharp instruments at very high speeds and limited access in an environment that is bathed in saliva and, in many instances, blood. Dental care professionals are at high risk of cross-infection while treating patients. The dental clinic is an environment where dis¬ease transmission occurs easily. Prevention of cross-infection in the dental clinic is, therefore, a crucial aspect of the dental practice, and dental clinic workers must adopt certain basic routines while practicing.