Neuron degeneration will be a system of operations in which the neurons lose its structure and functionality this results in the end of neurons. Neuron cells are basically responsible for gathering information, synthesizing the same information and passing appropriate signals, based on the information sent, to other nerve cells. There will be no particular involuntary relationship between handwriting patterns of a patient suffering from a neurodegenerative disease. It is known truth that handwriting of a patient can depict the intensity of the disease, it will also be taken as a symptom and detection tool, yet no standard theory or tool exists. Signature verification is an important biometric technique that aims to detect whether a given signature is forged or genuine. It is essential in preventing falsification of documents in numerous financial, legal, and other commercial settings