In olden days, the complexity of fabricating the mechanical components is higher and time consuming. Manufacturing industries normally use conventional methods like casting and forging process to shape components and use CNC machines to achieve final dimensions within the required tolerance. The difficulty in making components can be minimized by introducing the techniques for reduced setup time reduced machining time for increase in productivity and increase in accuracy and surface finish as a result of using 5- axis CNC VMC milling machining setup. But prior to start machining, a virtual simulation of the entire operations is to be carried out to check, verify and rectify the occurrence of collision, and the application of suitable parameters to achieve reduced cycle time. And this virtual simulation can be carried out through Mastercam software. This paper is focused on 4-axis finishing process of camshaft using 5-axis CNC VMC milling machine. This work involves geometric modeling of camshaft using Solid Works software. The model is then imported to Mastercam software for applying different methods and parameters to simulate the tool. Then the suitable parameters having collision free and reduced cycle time is taken into account. Then, the NC program is generated using the required post processor and program is entered to the 5- axis CNC milling machine to perform both roughing process and finishing process. Material used is Aluminum Alloy 6061. As per the experimental results, it has been observed that constant overlap spiral tool path for top part machining is selected and high speed tool path is selected for bottom part 3- axis rough machining and rotary 4 axis tool path for final finishing ensuring collision free and reduced cycle time. The cycle time resulted by Mastercam software is less than the cycle time resulted by the 5 axis CNC VMC milling machine. Then, the total machining time of camshaft as per the profile were found to be 5.83 hours and 52 seconds.