A Review: Design and Implementation of IOT Gateway
Today’s user needs a more fast and mobile way of devices to respond. The necessity of smart devices providing connectivity to the world at each second becomes as mandatory part of our life. Therefore the connectivity of a number of smart and intelligent devices rapidly grows each year. So that according to necessity an autonomous device connection should be required. One of the impressive and powerful solutions is known as the Internet of Things (IoT).The IoT is the network of Man smart physical devices which would be connected to each other that they could interact directly with each other and collect as well as exchange data. In this project, an IoT Gateway system based on ZigBee and Wi-Fi protocols according to the typical IoT application scenarios is presented. Wireless sensor networks (WSN) is the collection of different sensors with different protocols sends data to IoT Gateway which is responsible for the conversion of different protocols in standard format and also do the conversion of internet protocols and finally gave an implementation of prototyping system and system validation.
Published by: Pushpa N Methekar, Girish R. Talmale
Author: Pushpa N Methekar
Paper ID: V3I2-1228
Paper Status: published
Published: March 14, 2017
Android Based Digital Attendance Recording System
In this paper, we are focusing on developing this project, which will help the lecturers to take attendance easily, securely and will have less error. For this, we are implementing android based software for digital attendance recording system at teacher’s Android mobile phone and student’s Android mobile phone. This system will help lecturers to take attendance of the students using the android mobile phone, by using Bluetooth device with fingerprint authentication of a mobile phone, those who are present in the class, whose attendance will be marked. after that captured data will be sent to server database from where attendance list will be updated automatically on the server’s database, lectures will able to edit the attendance and easily get requested information. Thus, the project will reduce the workload of lecturer by providing them the android technology based platform where they will be able to take, manage, update and see the attendance of students with efficiency.
Published by: Mr. Satish H. Jadhav, Ashutosh B. Makone
Author: Mr. Satish H. Jadhav
Paper ID: V3I2-1227
Paper Status: published
Published: March 14, 2017
A comparative Docking Analysis of Non-carcinogenic DNA staining Dyes to propose the best Alternative to Ethidium Bromide
Fluorescent dyes that stain a cell’s DNA are used in live cell imaging as they allow for tracking of cell division, for the visualization and sizing of dsDNA restriction fragments, and for the examination of properties of the isolated DNA molecules. Conventionally, Ethidium bromide (EtBr) is the cationic dye used to visualize DNA after separating the fragments on Agarose Gel Electrophoresis. It is widely used due to the striking fluorescence enhancement it displays upon intercalation into the dsDNA at the minor groove. Although a highly sensitive stain, it is notoriously unsafe, not only is it a very strong mutagen, it may also be a carcinogen or teratogenic. Histopathological changes of Ethidium Bromide treated rats showed little degenerative changes characterized by glomerular and tubulointerstitial injury, nephrosis, synechia, necrotic changes, cirrhosis, and ischemia. Ethidium bromide revealed pronounced degenerative changes in ovarian histoarchitecture. The sequence of atretic changes involved nuclear degeneration, characterized by Chromatolysis, rupture, and dissolution of the nuclear membrane. Granulosa cells associated with degenerating follicle types (bilaminar, Multilaminar and graffian follicle) showed desquamation, cytolysis, and nuclear dissolution.Extensive vacuolation also occurred in these follicles. Only a few follicles reached the maturity. In most of the females, Graffian follicle failed to rupture, which led to failure in ovulation. This resulted in Sterility of the females.Hence need has arisen for now –carcinogenic and not- hazardous nucleic acid staining dyes.Our Present study has thus been aimed at finding out the non-carcinogenic DNA staining dyes and to compare their binding efficiency with DNA and find out which is the best DNA staining Dye which has least binding energy score and is non-carcinogenic as well. Hence now-a- days safer alternatives to EtBr are being sought after. A comparative docking study of six of such The interaction of EtBr and the six other alternative dyes (Crystal violet, GelRed, Hoechst 33258, Methylene blue, SYBR Green and GelGreen) with the ds-B-DNA were studied, their chemical structures were drawn using ChemSketch and the potential ligands were optimized using ArgusLab. Further, the docking studies of these DNA stains on a dsDNA molecule (1D49) was performed using AutoDock tools and their interaction with the DNA was visualized using Discovery Studio. The binding energies of Hoechst 33258 with the DNA was found to be better (-11.96 Kcal/mol) as compared to the other strains, thus suggesting its use as both a non-carcinogenic and highly sensitive alternative to EtBr.
Published by: Manisha Mathur, Parakh Sharma, Priyanka Yadav, Christy Joseph
Author: Manisha Mathur
Paper ID: V3I2-1226
Paper Status: published
Published: March 14, 2017
ANXA5 Gene: An Insilco approach for SNP analysis associated with RPL
Miscarriage is the most familiar pregnancy obstacle affecting up to 15% of all clinically recognized pregnancies. Annexin A5 gene is a well-recognized predisposition factor for recurrent spontaneous abortion. Annexin A5 is both Ca2+ and phospholipids binding protein that is localized at the surface of the placental syncytiotrophoblast layer and performs a vital role in anticoagulant function in the maternal blood at the inter villous space. It has been recently shown that polymorphisms in the promoter region of the annexin A5 gene (ANXA5) are significantly associated with RPL. The present study focuses on the comprehensive analysis of the functional and structural impact of all known SNPs of ANXA5 gene by using computational approaches. Comprehensive analysis was performed to filter the most probable mutation that might be associated with RSA. It resulted in identification of SNPs which are most deleterious and disease associated. The study reveals that these two rs111418524, rs41278081 SNPs have more significant effect on structure and function of the protein.
Published by: Nasreen Sultana, Jeevan Amos. S, Kasturi. K
Author: Nasreen Sultana
Paper ID: V3I2-1221
Paper Status: published
Published: March 13, 2017
Insilico studies on Taste Receptor Gene (Tas2r38) and Tas2r38 Protein interaction with Ligands PTC and PROP using Docking Approach
The G protein-coupled receptor(gpcr)Tas2r38 is a bitter taste receptor that can respond to bitter compounds such as phenylthiocarbamide(PTC) and 6-n-PROPylthiouracil(PROP).This receptor was chosen because of its haplotypes (based on three residue site polymorphism) htas2r38pav, htas2r38avi are known to have a dramatically different response to ligands PTC and PROP. A docking study is performed to propose the best affinity between ligands PTC & PROP against the various active site of tas2r38 protein. The 3D structure of tas2r38 bitter taste receptor was predicted using GPCR-I-TASSER. The interaction of tas2r38 protein with ligands PTC & PROP were studied, their chemical structures were drawn using Marvin sketch and the potential ligands were optimized using pyrx. Meta pocket tool was used to predict the binding sites for htas2r38pav, htas2r38avi bound to Ptc & PROP respectively. Further, the docking studies of tas2r38 protein with Ptc & PROP was performed using pyrx tools and their interaction with the tas2r38 protein was visualized using discovery studio. The ligand PTC & PROP was docked on the protein PAV at the active sites 108,112,199 & 266 which showed a docking efficiencies of -4.6,-4.5,-4.7 &-5.3 respectively. Also, these ligands were docked on another haplotype AVI at the active sites 198,262,266 which showed a docking efficiencies of -4.7,-5.1, respectively. On the basis of their binding scores, it was predicted that the ligand PTC has a higher binding affinity to the haplotypes PAV and AVI as compared to the ligand PROP.
Published by: Manisha Mathur, Parakh Sharma, Faiza S. Khan, Mrunmai Pednekar
Author: Manisha Mathur
Paper ID: V3I2-1216
Paper Status: published
Published: March 11, 2017
A Review on Distribution Feeder Reconfiguration Methods
Distribution Feeder Reconfiguration (DFR) is a critical analysis to optimize and control the distribution system and an important function of distribution automation system. Distribution feeders are configured radially. Their configurations may be varied with manual or automatic switching operations so that all of the loads are supplied with acceptable voltage levels, reduce power loss and enhance power quality. DFR also relieves the overloading of the network components. The change in network configuration is performed by opening sectionalizing (normally closed) and closing tie (normally open) switches of the network. These switchings are performed in such a way that the radiality of the network is maintained and all of the loads are energized. This paper presents a review of Distribution Feeder Reconfiguration (DFR) methods which includes heuristic and genetic algorithm approach.
Published by: K. K. S. V. V Prakasa Rao, V. C Veera Reddy
Author: K. K. S. V. V Prakasa Rao
Paper ID: V3I2-1215
Paper Status: published
Published: March 11, 2017
