Recent advancement in adipose stem cell-based bone tissue engineering
Adipose stem cells (ASCs), a variety of mesenchymal stem cells (MSCs) are an essential element within bone tissue engineering (BTE). ASCs offer several advantages in isolation, culturing, maintenance, differentiation, repair, etc. Because of all these advantages of ASCs along with high paracrine activity, lacking major histocompatibility complex class II expression autologous ASCs are attracted towards treatment for organs damaged due to disease or injury and also in regenerative medicine. Bone is a very compound tissue and it takes part in various processes which include endocrine functions, hematopoiesis, mineral homeostasis and storage, body movement. Bone tissue engineering approaches involve combining cells and engineering materials with signaling molecules which is crucial for effective bone repair. ASCs are a vital element in BTE. BTE requires 3 important elements: (1) osteoprogenitor cells, (2) bioactive factors, (3) scaffold. In this review, we will be focusing on the recent discoveries which have employed the use of scaffolds, ASCs, bioactive factors in BTE. This review first outlined the advantages of ADCs in terms of isolation, culture, differentiation, etc. The different Growth factors involved in osteogenesis, which are the key segments in BTE. The available and recent innovations in the biological, mechanical, and structural necessities in the design of a profitable scaffold and their effects, which is succeeded by a summary of regular materials intended for scaffold fabrication were then briefed.
Published by: Raksha M., Shravani K. S.
Author: Raksha M.
Paper ID: V7I3-1456
Paper Status: published
Published: May 29, 2021
Recent trends in microfluidics-based skin-on-a-chip models and applications
Skin in the human body plays a major role being a dermal barrier, maintains homeostasis, and is a vital route for the administration of cosmetics and pharmaceutical formulations. Currently, skin diseases are also posing a threat globally, being ranked fourth among non-fatal diseases. Preclinical studies of drugs and therapeutics are required to be performed at a faster rate and ensure that the results obtained are accurate. Using conventional methods of animal testing is leading to high failure rates and an expensive drug development process. To circumvent these limitations, miniaturized microfluidic devices are gaining immense popularity with respect to diagnostics, biomedical research, and drug testing. Skin-on-Chip is one of the micro-engineered biomimetic platforms that can be used as an alternative to animal testing in preclinical studies. This review gives a brief overview of the limitations in the conventional drug development process. It gives clear insights into the general designing of the skin-on-chip device and collates recent developments that skin-on-chip models are subjected to, with an overview of the side effects testing of sorafenib using the skin-on-chip model. Integration of microsensors is also summarized in this review. The use of iPSCs and Skin-on-Chip in a combination resulting in better in vitro skin models is also highlighted. Further, this review gives information about the utilizations of Skin-on-a-Chip models in diffusion studies, wound healing, and progress in precision medicine tailored to the person. Finally, the potential challenges that have to be overcome for its widespread utilization are elucidated.
Published by: Shravani K. S., Pushpa Agrawal, Raksha M.
Author: Shravani K. S.
Paper ID: V7I3-1455
Paper Status: published
Published: May 29, 2021
Communication using VLC
Visible Light Communication technology is considered complimentary to Radio Frequency (RF) technology. The current Wi-Fi network uses Radio Frequency waves, but the usage of the available RF spectrum is limited. Therefore, a new technology, Li-Fi has come into the picture. Light Fidelity (Li-Fi) based Visible Light Communication system appears to have enhanced wireless capability to realize IoT, 5G Cellular Systems, and many more. Li-Fi is a recently developed technology.
Published by: P. Sai Sravya, B. Nilesh, Ch. Naresh, D. Shashank, B. Balaji Naik
Author: P. Sai Sravya
Paper ID: V7I3-1528
Paper Status: published
Published: May 28, 2021
The need for digital transformation in business
There was a time in business, where business as usual was good enough. Now no more. Where we are going good enough is dead and dying. In a world where everything is connected, there is only one major space to innovate, which is the digital transformations inside the organization. The organizations which are not digitally transforming are getting out of business. The research paper aims to identify, describe the impact of digital transformation of business in India and describe the key drivers of strategic business management development in the light of the recent waves of digital transformation. This research paper presents an overview of the existing literature, which is there concerning digital transformation. The research results from professional associations as well as the existing body of the recognized publishers were considered for making the research. Furthermore, we have conducted expert interviews as well as the market data where it was available.
Published by: Sajan Mathew
Author: Sajan Mathew
Paper ID: V7I3-1511
Paper Status: published
Published: May 28, 2021
Design of autonomous line follower robot with obstacle avoidance
This paper shows the design and implementation of the Line Follower Robot and its ability to select the desired line among the black and white lines. This can be combined with different colors. Since each color has its own distinct property, the robot can therefore easily differentiate among different colors and possess the ability to detect the presence of an obstacle and choose the other path to find its target. It is programmed in such a way that instructions are given to the robot which senses a line and attempts to move towards the target. The robot can easily move along very congested curves as it continuously data from the sensors. This robot avoids collision and it can detect collision with an obstacle sensor and hence reaching the target. The proposed system can be implemented in any commercial, industrial, medical, and also in educational labs
Published by: Kumar Rishabh
Author: Kumar Rishabh
Paper ID: V7I3-1547
Paper Status: published
Published: May 28, 2021
Blockchain based data privacy preservation for financial sector
Whenever people want to store information over the internet in cloud storage, security is the primary thing that comes to mind. There are more chances that anyone will leak such data if we store a data as it is or transfer a data as it is over the internet.In request to decrease the demand of monetary item data update among multi organizations, oversee multi-dimensional and broadened monetary information encryption, improve the traceback capacity, we propose a blockchain-based financial area.
Published by: Prathiba K. C., S. G. Raghavendra Prasad
Author: Prathiba K. C.
Paper ID: V7I3-1545
Paper Status: published
Published: May 28, 2021
