How can iPSC-Derived Therapies Complement Traditional Burn Treatments, such as Skin Grafts and Wound Dressings?
Burn injuries pose significant challenges in clinical management, often resulting in long-term complications like scarring and impaired wound healing. Traditional treatments have limitations, spurring exploration into innovative modalities. Induced pluripotent stem cells (iPSCs) offer promise in regenerative medicine by providing personalized and autologous cell sources. This paper assesses iPSC-derived therapies' potential to complement traditional burn treatments. iPSCs, generated from patient somatic cells and differentiated into skin cells, offer a tailored approach to wound healing. Their immunomodulatory properties can mitigate inflammation and reduce rejection risk in allogeneic transplantation. Despite challenges, iPSC-based therapies can revolutionize burn care, improve outcomes, and enhance burn survivors' quality of life. Continued research and advancements in iPSC technology are essential for realizing these approaches' full potential in clinical practice. Burn injuries present complex wound management challenges, requiring innovative approaches. This paper evaluates iPSC-derived therapies' integration into two key aspects of burn treatment: skin grafting and wound dressings. Traditional skin grafting faces limited availability and functional outcomes, which iPSC technology may address by providing patient-specific, functionally enhanced graft material with reduced rejection risk. Similarly, traditional wound dressings have limitations impacting their effectiveness in burn treatment. Advanced dressings incorporating iPSC-derived cells offer active participation in wound healing, promoting tissue regeneration, and minimizing scarring. Preclinical and clinical studies demonstrate iPSC-derived therapies' efficacy in enhancing keratinocyte migration, angiogenesis, and wound closure. These findings underscore iPSC-based therapies' potential to revolutionize burn treatment by addressing key challenges and improving patient outcomes. Future research should focus on refining protocols, conducting large-scale clinical trials, and navigating regulatory pathways to facilitate widespread adoption, ultimately enhancing the quality of life for burn survivors. Addressing scalability, cost, and ethical considerations is paramount for successful integration into clinical practice, requiring collaborative efforts between researchers, clinicians, regulators, and stakeholders.
Published by: Gunnika Jain
Author: Gunnika Jain
Paper ID: V10I3-1203
Paper Status: published
Published: June 19, 2024
Complexities of Social Mobility: A Multifaceted Analysis of Factors Influencing Workers in Unorganized Sectors
Purpose: The study of challenges encountered by the workers belonging to the unorganized sector leads to have greater understanding in order to provide awareness among the workers possessed with un-skilled, semi-skilled, and high-skilled. Present workers in the unorganized sectors are not protected and monitored by the government due to that more job-related exploitation and violations are faced by the workers. This is considered essential to provide tailored content for workers belonging to different categories such as Minor ranchers, landless rural laborers, and tenant farmers. The study is done with the intention of identifying challenges faced by these three groups of workers. Design/Methodology/ Approach This was conducted by using an exploratory research design on a sample size of 414 comprising 138 respondents from three categories of workers belonging to unorganized sector selected, namely Minor ranchers, landless rural laborers, and tenant farmers. The study used a convenience sampling technique; the data was collected with the help of a formal interview schedule. Likert scale statements were used to record the responses ranging from highly agree to highly disagree and multiple discriminant analysis was applied for data processing. Findings The study found that Minor Ranchers workers are not getting reasonable wages and advances, and Ransome is paid to middlemen by the land ranchers, and wages are paid on time to them. The Landless rural laborers are not receiving wages on time and insufficiency in getting workers at the time of harvesting created more work burden. Tenant farmers need to pay for the length of working hours and for overtime. Originality Although studies on complexities and challenges faced by unorganized sector workers are available, studies on the specific category of workers of the unorganized sector are found to be rare. This research finding will provide sufficient insight to the researchers and academicians as well as to the workers belonging to the different groups with educational backgrounds.
Published by: K Pushpalatha, Dr. A Punnavanam
Author: K Pushpalatha
Paper ID: V10I3-1202
Paper Status: published
Published: June 14, 2024
Automatic Rain Sensing Windows
The aim is to create an automatic rain-sensing window that closes when it rains. The concept of sensing rainwater to run a DC motor can be widely seen in the automobile industry. Wipers that start automatically after detecting rain are quite common in vehicles. However, not much research has been done regarding using this system for domestic use. By putting forward this idea we hope to incorporate these windows effectively in both homes and commercial buildings. Rain sensors, microcontrollers, DC motors, and Dual H-Bridge motor drivers are some of the components used in our work. The objective is to ensure that the technology behind these windows is reliable and increase the accuracy, accessibility, and dependability of the product by addressing any potential limitations or challenges that may arise. The aim is to create an automatic rain-sensing window that closes when it rains. The concept of sensing rainwater to run a DC motor can be widely seen in the automobile industry. Wipers that start automatically after detecting rain are quite common in vehicles. However, not much research has been done regarding using this system for domestic use. By putting forward this idea we hope to incorporate these windows effectively in both homes and commercial buildings. Rain sensors, Microcontroller, DC motor, and Dual H-Bridge motor driver are some of the components used in our work.
Published by: Shreya Vijay Wanwe, Vishnu R. Sonwane, Soniya P. Warade, Krupal V. Warale, Siddhant S. Wasnik, Vineet V. Wathurkar
Author: Shreya Vijay Wanwe
Paper ID: V10I3-1186
Paper Status: published
Published: June 14, 2024
Immediate loading of dental implants placed with Osseodensification technique in Maxillary Posterior region of jaw
Implant placement and immediate loading in maxillary posterior has always been a challenge because of various conditions like less dense bone, etc. Osseodensification has proven to be a superior technique to improve the overall success rate of implant restorations. This study is done on 28 patients with maxillary posterior missing tooth (n=14 each). The implant stability (using RFA method) and crestal bone levels are evaluated at the time of implant loading and at the end of 3 months. Osseodensification technique turns out to be the superior osteotomy preparation technique than conventional one in terms of stability and crestal bone loss in immediately loaded dental implants placed in maxillary posterior region.
Published by: Dr. Varsha Patil
Author: Dr. Varsha Patil
Paper ID: V10I3-1196
Paper Status: published
Published: June 10, 2024
Artificial Intelligence with Special Perspective on Finance Industry
Alan Turing first asked, "Can machines think?" in the 1950s, and artificial intelligence has existed ever since. Siri and Alexa on Amazon are now well-known. But the finance sector was the one that swiftly caught up with it. Technology is evolving at a rapid pace, and artificial intelligence (AI) is leading this change in the financial services sector. This rise has accelerated recently due to the development of big data, cloud computing, creative hardware, and quicker special-purpose systems. Algo trading, fraud detection, chatbots, market and regulatory compliance, market effect research, and stress testing are just a few of the many uses of artificial intelligence that are widely employed today. Financial services personnel struggle with the technology's inherent problems as well as its prospective benefits as this huge transformation takes place.
Published by: Diva Chhabra
Author: Diva Chhabra
Paper ID: V10I3-1188
Paper Status: published
Published: June 7, 2024
Peer Pressure and Decision-Making Among Adolescents: A Game Theory Perspective
Peer pressure is a critical factor affecting adolescents' choices, often leading to decisions that prioritize social conformity over personal benefit. A survey of adolescents (n=108, mean age=15.5 years) was administered to measure how peer pressure impacts decision-making in various social scenarios, particularly focusing on situations modeled by game theory concepts. The findings reveal that peer pressure significantly influences adolescents to make decisions that align with group expectations, even when such choices may not be individually optimal. The analysis indicates that students frequently choose to conform to peer expectations, which supports game theory predictions about cooperative and competitive behaviors in social dilemmas. The role of peer dynamics played in shaping adolescents’ decision-making process was suggested. The need for measures that can help adolescents develop better decision-making skills under peer pressure was highlighted. Valuable insight was provided for educators, parents, and policy-makers aiming to support adolescents in navigating complex social interactions.
Published by: Tejas Agarwal
Author: Tejas Agarwal
Paper ID: V10I3-1195
Paper Status: published
Published: June 6, 2024
