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Recent Papers

Review Paper

Dihydrofolate Reductase (DHFR): A Versatile Protein with Crucial Roles in Life and Disease

Dihydrofolate reductase (DHFR), a ubiquitous oxidoreductase, occupies a pivotal position in folate metabolism. This review presents a comprehensive analysis of DHFR's structure, catalytic mechanism, and diverse physiological roles. We highlight its essential function in purine and thymidylate biosynthesis, emphasizing its impact on DNA replication and cell proliferation. The review further explores the multifaceted implications of DHFR in disease: its exploitation in cancer chemotherapy through targeted inhibition, its role in bacterial antibiotic resistance, and potential associations with autoimmune disorders. Finally, we discuss emerging research avenues delving into novel DHFR inhibitors for cancer therapy, strategies to combat DHFR-mediated antibiotic resistance, and the exploration of DHFR gene polymorphisms in personalized medicine approaches for autoimmune diseases. This review underscores the critical role of DHFR in both normal cellular processes and various disease states, paving the way for future advancements in targeted therapeutic interventions.

Published by: Mayur Bagane, Dr. Rajesh Jorgewad, Goutam Jirage

Author: Mayur Bagane

Paper ID: V10I1-1208

Paper Status: published

Published: February 16, 2024

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Research Paper

The Transformative Impact of Artificial Intelligence on Employment: Opportunities, Challenges, and Solutions in the Global Landscape

This research paper delves into the current and future implications of Artificial Intelligence (AI) on employment, exploring its effects on job creation, transformation, challenges, and potential solutions. It examines the evolving landscape of employment in the context of AI, including the creation of new job opportunities, transformation of existing roles, societal implications, human-AI collaboration, ethical considerations, future skills, and education requirements. The paper underscores the importance of inclusive policies, lifelong learning, and global cooperation to navigate the complex interplay between AI and the labor market.

Published by: Divyaansh Gandhi

Author: Divyaansh Gandhi

Paper ID: V10I1-1212

Paper Status: published

Published: February 14, 2024

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Research Paper

The Evolution of Boxing

Boxing, as a combat sport, has been captivating audiences for centuries with its display of skill, power, and determination. Despite its popularity, boxing faces numerous challenges and controversies. This paper explores the evolution of boxing, from its ancient origins to its modern-day significance. It delves into the sport's rules, governing bodies, famous personalities, cultural impact, and the ethical issues it confronts. By examining these facets, we gain insight into boxing's enduring appeal and its potential future directions.

Published by: Angad Batra

Author: Angad Batra

Paper ID: V10I1-1209

Paper Status: published

Published: February 14, 2024

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Thesis

The expansion theory (Oasis of opportunities)

The Expansion Theory or also called "Oasis of opportunities" - states that for every problem (P) there is one or more corresponding solutions (Sn), more or less effective, such as to be able to nullify and/or neutralize that problem. Furthermore, for every effective solution submitted to that problem, there will be n Opportunities for people and/or communities of people.

Published by: Antonio Lobusto

Author: Antonio Lobusto

Paper ID: V10I1-1205

Paper Status: published

Published: February 12, 2024

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Research Paper

The Origin and Development of Jatra Theatre in Odisha

The performance Tradition of Folk Theatre and Traditional Folk Theatre forms of Odisha is as old as our civilization. There are many forms of Folk Theatre and Traditional Folk Theatre in the cultural sphere of Odisha. Jatra is one of the most popular forms of folk theatre that originated and developed from the religious and spiritualistic base of the Bhakti Movement. Now it has become a highly commercialized form of Odia Folk Theatre. It is all about its origin and gradual development. Abstracts: The performance Tradition of Folk Theatre and Traditional Folk Theatre forms of Odisha is as old as our civilization. There are many forms of Folk Theatre and Traditional Folk Theatre in the cultural sphere of Odisha. Jatra is one of the most popular forms of folk theatre that originated and developed from the religious and spiritualistic base of the Bhakti Movement. Now it has become a highly commercialized form of Odia Folk Theatre. It is all about its origin and gradual development.

Published by: Narottam Parida

Author: Narottam Parida

Paper ID: V10I1-1204

Paper Status: published

Published: February 12, 2024

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Research Paper

Ways to Enhance Airline Efficiency and Profitability

This research investigates various strategies and innovations aimed at enhancing airline productivity. It explores how operational enhancements, technological advancements, and environmentally sustainable practices can mitigate costs, boost production, and minimize adverse environmental effects. The paper offers an overview of diverse approaches airlines can adopt to enhance their overall performance, drawing insights from case studies and industry trends.

Published by: Shlok Kapoor

Author: Shlok Kapoor

Paper ID: V10I1-1202

Paper Status: published

Published: February 12, 2024

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