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Review Paper

A review on Diabetes Mellitus with their types, complications, treatment, and research approach

This paper has presented about Diabetes Mellitus and its types. It also discussed cure and treatment of diabetes, and complications which are linked to badly controlled diabetes. It is a common misconception among the people that diabetes is not a serious disease, but in reality, it affects overall life expectancy. In recent years, many types of research in the field of Biomedical describe the effect of Diabetes, and due to this disease life rate decreases. Diabetes is a group of metabolic disease in which a person has high blood glucose over a long period of time, because of inadequate production of insulin hormone from the pancreas. Many of the complications are arises due to badly controlled diabetes so better and proper cure is very necessary. Nowadays many researcher and scientist are working to find the best technique for controlling this disease and this may be helpful for better treatment for the diabetes mellitus in the future.

Published by: Husna Parveen

Author: Husna Parveen

Paper ID: V4I4-1211

Paper Status: published

Published: July 11, 2018

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Research Paper

Management of occupational stress: A study of employees dealing with customers in public and private sector banks

Workplace stress is not a disease. Workers’ responses to stressors may be positive or negative depending upon the type of demands placed on them, the amount of control they have over the situation, the amount of support they receive and the individual response of the person. In most of the cases, people adjust to stress and are able to continue to perform their normal work duties

Published by: Dr. Manvinder Tandon, Deksha Verma

Author: Dr. Manvinder Tandon

Paper ID: V4I4-1177

Paper Status: published

Published: July 11, 2018

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Research Paper

Development and Validation of Stability-indicating method for the determination of Pregabalin by RP-HPLC

Pregabalin is an anticonvulsant drug used for neuropathic pain. Pregabalin binds to the alpha-2-delta subunit of the voltage-gated calcium channel in the central nervous system. The aim of the present study was to develop the stability indicating, highly accurate precise and linear method for a related substance of the Pregabalin through the reverse phase HPLC and to validate as per the current ICH guideline. The optimize method uses a reverse phase column, Inertsil ODS 3V (250 mm × 4.6 mm, 5µ), mobile Phase of Di-ammonium hydrogen phosphate buffer (6.5 ± 0.05) and Acetonitrile through gradient flow rate of 0.8 ml/min. Keeping the column at temperature 25°C and using the sample amount 20 µL and detected all the impurities at 210 nm by the UV detector. In the developed method, elution of Pregabalin was at 11.5 min and all the eluted impurities were well separated and met the system suitability criteria. The precision is exemplified by a relative standard deviation of 1.4%. Method percentage mean recoveries of all the impurities are within the range (90.0% to 115.0%) as per the protocol. The method was found to be robust. Linearity coefficient for all Impurities was more than 0.999. The LOD obtained was 0.004% and LOQ is 0.012%. Stability-indicating forced degradation established studies to show results that there was no interference of any degraded products or external environment. A new highly accurate, precise and stability indicating method was developed for a related substance of Pregabalin with all the impurities well separate from the degradation product of Pregabalin.

Published by: Shweta More, Pratima Tatke

Author: Shweta More

Paper ID: V4I4-1205

Paper Status: published

Published: July 10, 2018

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Others

Present day education with reference to the present youth

Education is the essence of overall development. It is the basic need for living a satisfactory life. In the present scenario, a true education is the one which helps one to live a value based life with a touch of practical aspect. There has to be the development of head, heart, and hand for the overall development of a human being. The basic question is are we giving right education or just creating machines who deteriorate the meaning of a good human resource. Is the youth of the nation happy with the education system, why are we not able to have classrooms with creative thinking and innovative youths. A revolution is needed to bring out the best, which can be indeed done by overhauling the process of education which will produce game changers in the global market.

Published by: Runa Paul

Author: Runa Paul

Paper ID: V4I4-1188

Paper Status: published

Published: July 9, 2018

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Review Paper

Working width: The forgotten dimension

The primary concern of the clinician is the 3-dimensional cleansing of the root canal system. The length of the root canal is a dimension which has been studied since long. But advancements in the imaging techniques and growing research has shown that the apical third of the root canal system has varying shapes that can lead to difficulties in the efficient cleaning & complete elimination of bacteria and debris. This article attempts to review various aspects related to the apical third dimension, techniques & methods presently available for its gauging, factors affecting the measurement and instruments or systems which claim a 3-dimensional cleaning and shaping of the apical third.

Published by: Dr. Pradnya V. Bansode, Dr. M. B. Wavdhane, Dr. Seema D. Pathak, Dr. Hardik Rana, Dr. Vaishali U. Bhalerao

Author: Dr. Pradnya V. Bansode

Paper ID: V4I4-1189

Paper Status: published

Published: July 9, 2018

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Research Paper

Effect of microsystin toxicity on Nain (Cirrhinus mrigala H.)

Microcystis aeruginosa, cyanobacteria are frequent components of much fresh water marine ecosystem which often produce a hepatotoxin called microsytin. The toxin adversely affects the aquatic life forms, in the present study, its effect on Nain (Cirrhinus mrigala) was observed in biological parameters. In the fishes, the serum calcium after exposure to an acute concentration of microcystin for 96h, the values decreased significantly (P=0.05) to 9.9 mg 100 ml-1 compared to control (12.6 mg 100 ml-1). The acute exposure of microcystin also decreased the serum protein from 7.3 to 4.8. The fish showed hypercholesterolemia on exposure to acute and lethal concentrations of microcystin for 96h and both short (15-30 days) and long (45-90 days) term, respectively. The antioxidants, SOD activity did not change significantly in the liver, kidney or gills of fish that had been exposed to crushed cyanobacteria for 15 days at lethal concentration, however, the longer exposure (30 days) resulted in a significant increase (P=0.05) in the SOD activity in liver but induction in kidney and gills were not significant.

Published by: Madhumita Srivastava, Arun Kumar Srivastava

Author: Madhumita Srivastava

Paper ID: V4I4-1204

Paper Status: published

Published: July 9, 2018

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