Pain is a very common and most stressful experience which a child faces during chemotherapy. Children with cancer need frequent pharmacological interventions to manage pain. As cancer is a chronic condition and cancer treatment-related symptoms like pain are reported by child and parents frequently. It is a known fact that cancer treatments are long term care which is associated with many side effects. This study aimed to examine the pain perceived by children with cancer. The study was conducted using a descriptive correlational design on 125 children who met the inclusion criteria using purposive sampling technique. Data was collected using Demographic and clinical variables Proforma and pain was assessed using the Wong Bakers Face Pain Rating Scale. The findings revealed that the pain experienced by children with cancer during chemotherapy was 64.8%. There was no significant association between Selected Demographic Variables of Children and Pain (p>0.05).