This is to report a single K/C/O Splenomegaly experiencing benefits of Siravyadh for splenomegaly as well as Coivd-19 during pandemic with supportive internal medication’s. Splenomegaly is an enlargement of the spleen which is compared to “Plihavrudhi” in Ayurveda. As per modern science surgical removal of the spleen is the last option for splenomegaly. the experience of one Case reported here showed the effect of Siravyadh to prevent splenomegaly and its recurrence. This case was mainly treated with a surgical procedure in Ayurveda called Siravyadh every monthly scence 1997 along with snehan Sweden followed by matra basti once in a year for 7 days with internal medication vardhaman pippali as rasayan and mahasudarshan Kadha 15ml × BD for 21 days. This cycle was repeated after every 3 months. As we know Covid - 19 (SARS- cov2), viral diseases caused by novel Coronavirus Impacted 220 countries in 2019-20 / 2020-21. SARS - Covid - 19 virus mostly affects the lungs first and then it affects blood parameters (changes in D - Dimer, WBC, CRP, ESR, etc ....) in this case it was found that Spleenomegaly was reduced with associated signs and symptoms and no recurrence was found. as well the patient is prevented from getting Covid - 19 infection although he is exposed to the covid positive patient.