In the acid-base titrations, standard synthetic indicators are used to exhibit color change at different pH intervals. Anthocyanins (natural color pigments) in plants exhibit color changes with pH variations. The aim of this study is to investigate the activity of plant extracts, Rosa indica and Rubus occidentalis, to replace the synthetic indicators. Synthetic indicators cause chemical and environmental pollution, are toxic, expensive and rarely available. Methanolic extracts of Rosa indica and Rubus occidentalis exhibit sharp and intense color change in comparison to the standard synthetic indicators phenolphthalein and methyl orange. Herbal indicators are pollution-free, non-toxic, easily available and cost-effective.