Bio-signal processing and analysis holds great significance in present day medical practice. In recent years, many processing techniques and different algorithms have been developed to help doctors to find new information added in bio- signals which is not easily noticeable in the raw data and hence aid in diagnosis of any ailments. Bio-signal processing is a rapidly evolving field with new processing technique coming out every other day which in turn makes it more and more difficult to be up to date. Signals format, algorithms implementation and comparison, artifacts and various other aspects make the learning of this field a long-drawn process, and in many situations plenty of software components are required to process or visualize bio-signals. In this paper we discuss open sourced, bio signal processing software packages that offer a variety of bio-signal processing algorithms: domain transforms, filtering, wave detection, basic operators, exchange signals format readily in their modules. The objective of this paper is to become an easily referable tool shed that discusses various options of software packages in brief for medical practice or biomedical educational purposes and to evaluate its compatibility with any architecture.