The following paper is a qualitative research study on the methods that can be used to safeguard and secure the supply chain of the pharmaceutical industry. This is an exceptionally difficult task, taking into consideration, the existence of counterfeit drugs and their growing footprint over the rest of the world. This has also led to an obligatory urgency to authenticate and secure supply chains against counterfeit drugs. This article studies the scope of management information systems, particularly RFID, in facilitating such precautionary measures. The main aim of this paper is to study the applications of the RFID technology in other developed countries which could possibly help the other nations to adopt such strategy and immunize their pharmaceutical industry.