The Cnidarian Hydra has been extensively used as a model organism studying the teratogenic and toxic potential of numerous toxins throughout the years and are more recently growing in popularity to assess the impacts of environmental pollutants. Hydra is an appropriate bioindicator species for use in environmental assessment owing to their easily measurable physical (morphology), biochemical (xenobiotic biotransformation; oxidative stress), behavioural (feeding) and reproductive (sexual and asexual) endpoints. Pharmaceuticals enter natural waters through sewage effluent and landfills and present an unknown risk to aquatic species including freshwater invertebrates. The cnidarian Hydra has been widely used to assess the acute toxicity of freshwater pollutants, but very little is known about pollutant accumulation by this animal. This study was conducted to study the effect of commonly used drugs, Paracetamol and Acetylsalicylic acid (Aspirin) on the morphological and physiological working of Hydra Vulgaris. The Hydra was exposed to 4 different concentrations of each drug for 24 hours and then observed for morphological and physiological changes.