This paper is published in Volume-4, Issue-4, 2018
Area
Pharmaceutical Chemistry
Author
Lincy Joseph, Mathew George, Jinijith S.
Org/Univ
Pushpagiri College of Pharmacy, Perumthuruthy, Thiruvalla, Kerala, India
Keywords
Antibacterial, Gram positive, Gram negative, 1,3,4-Oxadiazole
Citations
IEEE
Lincy Joseph, Mathew George, Jinijith S.. Synthesis, characterization, and evaluation of Antibacterial activities of 2,5-disubstituted 1,3,4-Oxadiazole derivatives, International Journal of Advance Research, Ideas and Innovations in Technology, www.IJARIIT.com.
APA
Lincy Joseph, Mathew George, Jinijith S. (2018). Synthesis, characterization, and evaluation of Antibacterial activities of 2,5-disubstituted 1,3,4-Oxadiazole derivatives. International Journal of Advance Research, Ideas and Innovations in Technology, 4(4) www.IJARIIT.com.
MLA
Lincy Joseph, Mathew George, Jinijith S.. "Synthesis, characterization, and evaluation of Antibacterial activities of 2,5-disubstituted 1,3,4-Oxadiazole derivatives." International Journal of Advance Research, Ideas and Innovations in Technology 4.4 (2018). www.IJARIIT.com.
Lincy Joseph, Mathew George, Jinijith S.. Synthesis, characterization, and evaluation of Antibacterial activities of 2,5-disubstituted 1,3,4-Oxadiazole derivatives, International Journal of Advance Research, Ideas and Innovations in Technology, www.IJARIIT.com.
APA
Lincy Joseph, Mathew George, Jinijith S. (2018). Synthesis, characterization, and evaluation of Antibacterial activities of 2,5-disubstituted 1,3,4-Oxadiazole derivatives. International Journal of Advance Research, Ideas and Innovations in Technology, 4(4) www.IJARIIT.com.
MLA
Lincy Joseph, Mathew George, Jinijith S.. "Synthesis, characterization, and evaluation of Antibacterial activities of 2,5-disubstituted 1,3,4-Oxadiazole derivatives." International Journal of Advance Research, Ideas and Innovations in Technology 4.4 (2018). www.IJARIIT.com.
Abstract
Lincy Joseph, et al.: Antibacterial activity of 2,5-disubstituted 1,3,4-Oxadiazole derivatives Synthesized five 2,5-disubstituted 1,3,4-Oxadiazole derivatives. The target compounds J1 – J5 were obtained by treating aromatic acid ester hydrazide derivative and β-Benzoyl propionic acid derivatives using concentrated sulphuric acid as a dehydrating agent. They were purified and characterized by IR, NMR, and Elemental Analysis. The compounds were further subjected to antibacterial study against gram positive and gram negative strains. Compounds J1 and J2 exhibited good antibacterial activity and compounds J3 and J4 were found to have moderate antibacterial activity compared to standard drug ciprofloxacin (30mcg).
