An effective vaccine is needed to halt the proliferation of SARS-CoV-2 that is: Severe Acute Respiratory Syndrome Coronavirus-2. An RNA vaccine is a type of vaccine that uses a copy of a natural chemical called messenger RNA (mRNA) to produce an immune response. COVID-19 BNT162b1 mRNA vaccine has been proved omnipotent enough for eliciting robust CD4+ and CD8+ T Cell responses and powerful antibody responses. COVID-19 mRNA vaccine can make fake versions of the viral protein especially, S antigenic protein but, potent enough to elicit a primary immune response against the COVID-19 virus. T Cells and commendatory cytokine retaliation induced by the BNT162b1 mRNA vaccine propose that it has a future to protect against SARS-CoV-2 Keywords: SARS-CoV-2; COVID-19 BNT162b1 mRNA Vaccine; Spike Antigenic Protein; Protection Against SARS-CoV-2.