This paper investigates the intricate strategies employed by multinational corporations (MNCs) to harness human psychology in advertising campaigns aimed at specific target audiences. Through an analysis of various psychological factors, including emotional appeal, social proof, scarcity and urgency, color psychology, cognitive biases, storytelling, personalization, neuromarketing techniques, and behavioral economics, the study examines how MNCs have evolved their marketing methodologies to integrate psychological principles. By delving into empirical examples and theoretical frameworks, the research illuminates the symbiotic relationship between economics and psychology in modern marketing strategies, highlighting how leveraging psychology as an asset can enhance profitability and foster business expansion for MNCs.