Now these employees, so-called patients came to the Occupational Therapist for treatment. Then Occupational Therapists first do the treatment of pains by using some physical Modalities as well as an Activity program. So it is very necessary for Industrial area that they should have a standard Occupational Therapy Ergonomic Advice for avoiding spinal problems. So the persons who are working in an industrial set-up will have a fruitful life and pain-free working environment. Presently in industrial set up, 90% (ninety percent) of persons are suffering from different problems. Among them approximately more than 60%(sixty percent) persons are having low backache, neck pain. Hence, it was decided to conduct this study as there is very little research work on this industrial population. A standard Ergonomic Advice of Occupational Therapy would be developed for the subjects with Low back pain. Post Test Comparison- • Independent Variables- Interventions- a) Activities and Exercises b) Ergonomic Advice 2) Dependent Variables- a) Pain b) Unable to perform an activity related back pain 3) Subjects-50 subjects are randomly selected from particular age group. Clinical Analysis clearly shows excellent improvement in persons working in an industrial set up after a successful intervention of Standard Occupational Therapy Ergonomic Advice, which includes Occupational Therapy activities and exercised, Occupational therapy Do’s and Don’t’s and Ergonomic advice. Result of this research is accepted hypothesis that use of Standard Occupational Therapy Ergonomic Advice which includes Occupational Therapy treatment, Do’s and don’ts and Ergonomic advice tremendously reduced symptoms of a low backache in persons working with Industrial set up. These persons are more happily doing their work and also with pleasure. Among four questionnaires, for 4 questions means for Four types of complaints, persons(subjects) got relief.