Lateral epicondylitis is one of the commonest musculoskeletal conditions. The etiology of lateral epicondylitis is poorly understood. In spite of long duration for treatment protocol recurrence rate is common. Objective: The present study was undertaken to compare the effect of Maitland mobilization and conservative treatment in lateral epicondylitis. Method: 60 subjects diagnosed with lateral epicondylitis were included in the study. Functional status of patient was evaluated using upper extremity functional index scale. The data was collected by questionnaire form and was analyzed using SPSS 14.0 and graph pad 6.7 version. Correlation of pain and hand grip was done using Pearson correlation coefficient. Result: 80% of cases were in the age group between 30-40 years and 20% were more than 40 years. 33.33% was males and 66.66% females. The mean pain on was in group A was 3.43 and in group B it was 4.2 by the end of 9 th week. Mean pain free grip strength improved in group A 19.96 as compared to group B 16.36 by end of 9th week. Mean upper extremity functional index showed significant improvement in group A as compared to group B. In occupation wise distribution 33.33% subjects were housewives, 20% were clerks. In hand dominance 91.66% were right-handed and 8.33% were left handed. Conclusion: From the present study it is concluded that Maitland mobilization combined with conservative treatment is effective in management of lateral epicondylitis as compared to only conservative treatment.