Local reactive focal overgrowth is frequently found in the oral cavities. Different types of localized reactive lesions may occur on the gingiva, including focal fibrous hyperplasia, pyogenic granuloma, peripheral giant cell granuloma and peripheral ossifying fibroma (POF). The inflammatory hyperplastic lesion may be defined as “an increase in the size of an organ or tissue due to an increase in the number of constituent cells, as a local response of tissue to injury. Irritation fibroma clinically resembles as pyogenic granuloma, peripheral giant cell granuloma or odontogenic tumors, so radiographic and histopathological examination is essential for accurate diagnosis.