Schizophrenia is a chronic mental illness with the symptoms of disordered thought, behavior, and emotions. The illness affects approximately 1% of the world’s population and accounts for 1-2% of national health care costs in industrial countries. Cognition is impaired in most of the schizophrenic clients. This study was conducted to assess the effectiveness of virtual reality therapy upon cognition among schizophrenic clients. A study was conducted by using Pre Experimental research design at a selected private hospital, Chennai, South India with the Sample size of 35. Samples were chosen by using purposive sampling technique. Data were collected through an interview method by using Demographic Variable Proforma, Clinical Variable Proforma, Mini-mental status examination scale. Post-test cognition score of schizophrenic clients was higher (M=29.4, SD=1.76) than the pre-test cognition score (M=22.6, SD=1.48), which was statistically significant(*P<0.001). It can be attributed to the effectiveness of Virtual Reality Therapy on improving cognition. The above findings reveal that virtual reality therapy is effective in improving the cognition in schizophrenic clients.